Marc Ruel Selected Research

Prostheses and Implants (Prosthesis)

7/2020	Direct Implant of a Transcatheter Aortic Valve Prosthesis for Prosthetic Mitral Valve Endocarditis.
1/2020	Rationale and design of PROACT Xa: A randomized, multicenter, open-label, clinical trial to evaluate the efficacy and safety of apixaban versus warfarin in patients with a mechanical On-X Aortic Heart Valve.
4/2016	Enhanced freedom from prosthesis-patient mismatch with transcatheter aortic valve replacement: More to aortic regurgitation than meets the eye?
8/2015	Clinical Impact of Changes in Left Ventricular Function After Aortic Valve Replacement: Analysis From 3112 Patients.
4/2013	Comparison of hemodynamic performance of self-expandable CoreValve versus balloon-expandable Edwards SAPIEN aortic valves inserted by catheter for aortic stenosis.
1/2013	Current readings: status of tricuspid valve repair.
7/2012	Long-term evaluation of biological versus mechanical prosthesis use at reoperative aortic valve replacement.
12/2011	Heart valve prosthesis selection in patients with end-stage renal disease requiring dialysis: a systematic review and meta-analysis.
11/2010	Influence of the On-X mechanical prosthesis on intermediate-term major thromboembolism and hemorrhage: a prospective multicenter study.
6/2010	Urgent replacement of a mechanical mitral prosthesis in an anticoagulated patient with Bombay red blood cell phenotype.

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Marc Ruel Research Topics

Disease

30	Coronary Artery Disease (Coronary Atherosclerosis) 06/2022 - 02/2003
21	Myocardial Infarction 01/2022 - 02/2007
18	Hemorrhage 10/2019 - 10/2005
17	Heart Failure 09/2021 - 01/2004
14	Stroke (Strokes) 01/2022 - 06/2007
13	Atrial Fibrillation 01/2020 - 07/2004
12	Aortic Valve Stenosis (Aortic Stenosis) 01/2019 - 07/2006
10	Thrombosis (Thrombus) 07/2022 - 10/2005
10	Myocardial Ischemia (Ischemic Heart Diseases) 11/2020 - 02/2003
8	Coronary Disease (Coronary Heart Disease) 01/2019 - 02/2003
7	Ischemia 07/2021 - 08/2003
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 01/2006
6	Pathologic Constriction (Stenosis) 07/2022 - 08/2005
6	Infarction (Infarctions) 01/2016 - 08/2003
6	Diabetes Mellitus 01/2015 - 09/2004
6	Hypercholesterolemia 05/2012 - 08/2004
5	Thromboembolism 01/2020 - 09/2006
5	Hypertension (High Blood Pressure) 01/2018 - 01/2003
4	Cardiomyopathies (Cardiomyopathy) 09/2021 - 01/2014
4	Prolapse 10/2020 - 09/2010
4	Endocarditis 07/2020 - 09/2006
4	Acute Coronary Syndrome 09/2019 - 03/2009
4	Left Ventricular Dysfunction 08/2015 - 07/2004
4	Hyperplasia 09/2013 - 10/2005
3	COVID-19 01/2021 - 01/2020
3	Acute Kidney Injury (Acute Renal Failure) 07/2020 - 01/2013
3	Cicatrix (Scar) 01/2020 - 09/2013
3	Inflammation (Inflammations) 01/2020 - 01/2015
3	Aortic Valve Insufficiency (Aortic Regurgitation) 04/2017 - 04/2013
3	Neoplasms (Cancer) 11/2013 - 02/2010
3	Atherosclerosis 09/2013 - 09/2009
2	Mitral Valve Insufficiency (Mitral Regurgitation) 10/2020 - 08/2014
2	Death (Near-Death Experience) 07/2020 - 02/2015
2	Renal Insufficiency (Renal Failure) 07/2020 - 11/2019
2	Hypotension (Low Blood Pressure) 01/2020 - 01/2018
2	Genetic Risk Score 12/2018 - 11/2018
2	Disease Progression 11/2018 - 01/2018
2	Bundle-Branch Block (Fascicular Block) 11/2018 - 01/2017
2	Infections 03/2017 - 01/2014
2	Cardiac Sudden Death (Sudden Cardiac Arrest) 01/2017 - 02/2015
2	Rupture 12/2016 - 12/2013
2	Wound Infection (Wound Infections) 07/2015 - 10/2011
2	Ventricular Remodeling 01/2015 - 09/2009
2	Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve) 01/2013 - 08/2004
2	Peripheral Vascular Diseases (Peripheral Vascular Disease) 01/2012 - 10/2007
2	Heart Diseases (Heart Disease) 11/2010 - 01/2008
2	Pulmonary Hypertension 06/2007 - 03/2007
2	Spasm (Spasms) 02/2007 - 11/2004
2	Pain (Aches) 08/2006 - 10/2004
2	Reperfusion Injury 03/2004 - 08/2003

Drug/Important Bio-Agent (IBA)

9	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 07/2022 - 10/2005
9	Clopidogrel (Plavix)FDA Link 09/2019 - 10/2005
7	CollagenIBA 01/2020 - 02/2010
7	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2018 - 10/2007
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2012 - 02/2003
4	TicagrelorIBA 07/2022 - 01/2018
4	Proteins (Proteins, Gene)FDA Link 05/2012 - 02/2003
4	Arginine (L-Arginine)FDA Link 01/2010 - 06/2005
3	omega-Chloroacetophenone (Mace)IBA 01/2022 - 01/2006
3	Warfarin (Coumadin)FDA LinkGeneric 01/2020 - 07/2004
3	CreatinineIBA 01/2015 - 01/2012
3	ameroidIBA 03/2013 - 12/2007
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 04/2008 - 07/2002
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2008 - 08/2004
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2005 - 08/2004
2	MetalsIBA 12/2020 - 03/2015
2	HydrogelsIBA 01/2020 - 01/2015
2	Biomarkers (Surrogate Marker)IBA 04/2019 - 08/2016
2	Biocompatible Materials (Biomaterials)IBA 01/2017 - 01/2015
2	CytokinesIBA 01/2015 - 03/2004
2	Therapeutic UsesIBA 01/2015 - 05/2009
2	Polytetrafluoroethylene (Teflon)FDA Link 04/2012 - 09/2010
2	Insulin (Novolin)FDA Link 12/2007 - 02/2005

Therapy/Procedure

40	Therapeutics 07/2022 - 02/2003
39	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 06/2022 - 09/2004
19	Prostheses and Implants (Prosthesis) 07/2020 - 01/2004
14	Percutaneous Coronary Intervention 01/2022 - 12/2013
14	Transcatheter Aortic Valve Replacement 01/2019 - 01/2010
12	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2020 - 08/2003
8	Length of Stay 01/2019 - 10/2004
7	Sternotomy 03/2017 - 08/2005
6	Bioprosthesis 04/2013 - 03/2004
5	Stents 12/2020 - 03/2013
5	Injections 01/2020 - 11/2013
4	Myocardial Revascularization 07/2021 - 12/2018
4	Catheters 07/2020 - 06/2006
4	Thoracotomy 03/2017 - 08/2005
4	Cell- and Tissue-Based Therapy (Cell Therapy) 11/2010 - 01/2008
3	Transplantation 01/2016 - 11/2007
3	Drug-Eluting Stents 07/2015 - 10/2014
3	Contraindications 10/2012 - 03/2010
2	Home Nursing (Nursing, Home) 01/2021 - 01/2018
2	Patient Readmission 07/2020 - 01/2017
2	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2020 - 01/2013
2	Off-Pump Coronary Artery Bypass (Coronary Artery Bypass, Off Pump) 11/2019 - 01/2017
2	Sutures (Suture) 12/2016 - 09/2010
2	Blood Transfusion (Blood Transfusions) 01/2016 - 07/2015
2	Heart-Assist Devices 03/2015 - 02/2014
2	Ligation 01/2012 - 08/2003
2	Induced Heart Arrest (Cardioplegia) 03/2004 - 08/2003